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Nakamura, Yusuke
One or more keywords matched the following items that are connected to Nakamura, Yusuke
Item TypeName
Concept Cross-Sectional Studies
Concept Mice, Inbred C3H
Concept Models, Chemical
Concept Feasibility Studies
Concept Models, Molecular
Concept Mice, Transgenic
Concept Models, Genetic
Concept Mice, Inbred BALB C
Concept Mice, Inbred C57BL
Concept Mice, Nude
Concept Cohort Studies
Concept Linear Models
Concept Multicenter Studies as Topic
Concept Proportional Hazards Models
Concept Models, Animal
Concept Case-Control Studies
Concept Mice, Knockout
Concept Mice, Inbred MRL lpr
Concept Genetic Association Studies
Concept Mice
Concept Models, Statistical
Concept Logistic Models
Concept Validation Studies as Topic
Concept Disease Models, Animal
Concept Follow-Up Studies
Concept Models, Biological
Concept Prospective Studies
Concept Retrospective Studies
Concept Mice, SCID
Concept Mice, Inbred NOD
Academic Article Genome-wide cDNA microarray screening to correlate gene expression profiles with sensitivity of 85 human cancer xenografts to anticancer drugs.
Academic Article Gene-expression profiles of human tumor xenografts in nude mice treated orally with the EGFR tyrosine kinase inhibitor ZD1839.
Academic Article Association of solute carrier family 12 (sodium/chloride) member 3 with diabetic nephropathy, identified by genome-wide analyses of single nucleotide polymorphisms.
Academic Article Implication of allelic polymorphism of osteopontin in the development of lupus nephritis in MRL/lpr mice.
Academic Article Mouse homologue of a novel human oncofetal antigen, glypican-3, evokes T-cell-mediated tumor rejection without autoimmune reactions in mice.
Academic Article Genetic variations in the gene encoding ELMO1 are associated with susceptibility to diabetic nephropathy.
Academic Article Functional SNP in an Sp1-binding site of AGTRL1 gene is associated with susceptibility to brain infarction.
Academic Article A SNP in the ABCC11 gene is the determinant of human earwax type.
Academic Article Multiplex PCR-based real-time invader assay (mPCR-RETINA): a novel SNP-based method for detecting allelic asymmetries within copy number variation regions.
Academic Article A nonsynonymous SNP in PRKCH (protein kinase C eta) increases the risk of cerebral infarction.
Academic Article Genome-wide detection and characterization of positive selection in human populations.
Academic Article Association analysis of genetic variants in IL23R, ATG16L1 and 5p13.1 loci with Crohn's disease in Japanese patients.
Academic Article Genetically manipulated human embryonic stem cell-derived dendritic cells with immune regulatory function.
Academic Article Identification of a novel tumor-associated antigen, cadherin 3/P-cadherin, as a possible target for immunotherapy of pancreatic, gastric, and colorectal cancers.
Academic Article Proliferation potential-related protein, an ideal esophageal cancer antigen for immunotherapy, identified using complementary DNA microarray analysis.
Academic Article Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population.
Academic Article Japanese population structure, based on SNP genotypes from 7003 individuals compared to other ethnic groups: effects on population-based association studies.
Academic Article A model of prediction system for adverse cardiovascular reactions by calcineurin inhibitors among patients with renal transplants using gene-based single-nucleotide polymorphisms.
Academic Article A genome-wide association study identifies ITGA9 conferring risk of nasopharyngeal carcinoma.
Academic Article HLA-B*3505 allele is a strong predictor for nevirapine-induced skin adverse drug reactions in HIV-infected Thai patients.
Academic Article Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease.
Academic Article Single nucleotide polymorphism in ABCG2 is associated with irinotecan-induced severe myelosuppression.
Academic Article Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk.
Academic Article Enhanced RASGEF1A expression is involved in the growth and migration of intrahepatic cholangiocarcinoma.
Academic Article Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease.
Academic Article Association study of genetic polymorphism in ABCC4 with cyclophosphamide-induced adverse drug reactions in breast cancer patients.
Academic Article The association of a nonsynonymous single-nucleotide polymorphism in TNFAIP3 with systemic lupus erythematosus and rheumatoid arthritis in the Japanese population.
Academic Article Genome-wide association study of intracranial aneurysm identifies three new risk loci.
Academic Article Inactivation of fibroblast growth factor binding protein 3 causes anxiety-related behaviors.
Academic Article Phase I clinical trial using peptide vaccine for human vascular endothelial growth factor receptor 2 in combination with gemcitabine for patients with advanced pancreatic cancer.
Academic Article Functional SNP of ARHGEF10 confers risk of atherothrombotic stroke.
Academic Article Successful outcomes using combination therapy of interleukin-2 and interferon-alpha for renal cell carcinoma patients with lung metastasis.
Academic Article PADI4 polymorphism predisposes male smokers to rheumatoid arthritis.
Academic Article Identification of evidence suggestive of an association with peripheral arterial disease at the OSBPL10 locus by genome-wide investigation in the Japanese population.
Academic Article A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population.
Academic Article Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations.
Academic Article A genome-wide association study reveals susceptibility variants for non-small cell lung cancer in the Korean population.
Academic Article Impact of LIMK1, MMP2 and TNF-a variations for intracranial aneurysm in Japanese population.
Academic Article Genome-wide associations and functional genomic studies of musculoskeletal adverse events in women receiving aromatase inhibitors.
Academic Article Common variation in GPC5 is associated with acquired nephrotic syndrome.
Academic Article Case-control association study of 59 candidate genes reveals the DRD2 SNP rs6277 (C957T) as the only susceptibility factor for schizophrenia in the Bulgarian population.
Academic Article A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians.
Academic Article SNPs on chromosome 5p15.3 associated with myocardial infarction in Japanese population.
Academic Article Possible involvement of NEDD4 in keloid formation; its critical role in fibroblast proliferation and collagen production.
Academic Article Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus.
Academic Article ADAM8 as a novel serological and histochemical marker for lung cancer.
Academic Article Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma.
Academic Article A genome-wide association study identifies three loci associated with susceptibility to uterine fibroids.
Academic Article New pharmacogenetic test for detecting an HLA-A*31: 01 allele using the InvaderPlus assay.
Academic Article Genome-wide association studies of tuberculosis in Asians identify distinct at-risk locus for young tuberculosis.
Academic Article Genome-wide association study of epirubicin-induced leukopenia in Japanese patients.
Academic Article Evaluation of CYP2D6 and efficacy of tamoxifen and raloxifene in women treated for breast cancer chemoprevention: results from the NSABP P1 and P2 clinical trials.
Academic Article Genome-wide association meta-analysis identifies new endometriosis risk loci.
Academic Article Genome-wide association study identifies two susceptibility loci for exudative age-related macular degeneration in the Japanese population.
Academic Article Evaluating genetic risk for prostate cancer among Japanese and Latinos.
Academic Article Variants of C-C motif chemokine 22 (CCL22) are associated with susceptibility to atopic dermatitis: case-control studies.
Academic Article A genome-wide association study of nephrolithiasis in the Japanese population identifies novel susceptible Loci at 5q35.3, 7p14.3, and 13q14.1.
Academic Article A genome-wide association study identifies three new risk loci for Kawasaki disease.
Academic Article SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations.
Academic Article Functional SNPs in CD244 increase the risk of rheumatoid arthritis in a Japanese population.
Academic Article Variation in the DEPDC5 locus is associated with progression to hepatocellular carcinoma in chronic hepatitis C virus carriers.
Academic Article Identification of independent risk loci for Graves' disease within the MHC in the Japanese population.
Academic Article New sequence variants in HLA class II/III region associated with susceptibility to knee osteoarthritis identified by genome-wide association study.
Academic Article Disruption of fibroblast growth factor signal pathway inhibits the growth of synovial sarcomas: potential application of signal inhibitors to molecular target therapy.
Academic Article Lessons for pharmacogenomics studies: association study between CYP2D6 genotype and tamoxifen response.
Academic Article A genome-wide association study identifies SNP in DCC is associated with gallbladder cancer in the Japanese population.
Academic Article A genome-wide association study identifies novel susceptibility genetic variation for thyrotoxic hypokalemic periodic paralysis.
Academic Article A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B.
Academic Article Whole-genome sequencing and comprehensive variant analysis of a Japanese individual using massively parallel sequencing.
Academic Article Optineurin mutations in Japanese amyotrophic lateral sclerosis.
Academic Article Replication analysis of SNPs on 9p21.2 and 19p13.3 with amyotrophic lateral sclerosis in East Asians.
Academic Article Common variant near the endothelin receptor type A (EDNRA) gene is associated with intracranial aneurysm risk.
Academic Article PlatinumCNV: a Bayesian Gaussian mixture model for genotyping copy number polymorphisms using SNP array signal intensity data.
Academic Article Prostate cancer genomics, biology, and risk assessment through genome-wide association studies.
Academic Article A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population.
Academic Article Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.
Academic Article Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.
Academic Article Genome-wide association study identifies genetic determinants of warfarin responsiveness for Japanese.
Academic Article Genome-wide association study identifies variations in 6p21.3 associated with nevirapine-induced rash.
Academic Article Genome-wide association study for intracranial aneurysm in the Japanese population identifies three candidate susceptible loci and a functional genetic variant at EDNRA.
Academic Article IRX4 at 5p15 suppresses prostate cancer growth through the interaction with vitamin D receptor, conferring prostate cancer susceptibility.
Academic Article Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population.
Academic Article Association between HLA-B*4001 and lipodystrophy among HIV-infected patients from Thailand who received a stavudine-containing antiretroviral regimen.
Academic Article Genome-wide association study of hematological and biochemical traits in a Japanese population.
Academic Article Combined immunotherapy with low-dose IL-2 plus IFN-alpha for metastatic renal cell carcinoma: survival benefit for selected patients with lung metastasis and serum sodium level.
Academic Article Interstitial lung disease in gefitinib-treated Japanese patients with non-small-cell lung cancer: genome-wide analysis of genetic data.
Academic Article Genome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations.
Academic Article Lack of association between variations of PDE4D and ischemic stroke in the Japanese population.
Academic Article Association study of the polymorphisms on chromosome 12p13 with atherothrombotic stroke in the Japanese population.
Academic Article Development of new HLA-B*3505 genotyping method using Invader assay.
Academic Article Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population.
Academic Article Meta-analysis of published studies identified eight additional common susceptibility loci for Crohn's disease and ulcerative colitis.
Academic Article A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese.
Academic Article HLA-Cw*1202-B*5201-DRB1*1502 haplotype increases risk for ulcerative colitis but reduces risk for Crohn's disease.
Academic Article A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population.
Academic Article Merging pharmacometabolomics with pharmacogenomics using '1000 Genomes' single-nucleotide polymorphism imputation: selective serotonin reuptake inhibitor response pharmacogenomics.
Academic Article A genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma.
Academic Article Association of common variants in TNFRSF13B, TNFSF13, and ANXA3 with serum levels of non-albumin protein and immunoglobulin isotypes in Japanese.
Academic Article Nucleotide pyrophosphatase gene polymorphism associated with ossification of the posterior longitudinal ligament of the spine.
Academic Article Correlation of allelic losses and clinicopathological factors in 504 primary breast cancers.
Academic Article Single-nucleotide polymorphisms in the class II region of the major histocompatibility complex in Japanese patients with immunoglobulin A nephropathy.
Academic Article Identification of 46 novel SNPs in the 130-kb region containing a myocardial infarction susceptibility gene on chromosomal band 6p21.
Academic Article Comparison of gene-expression profiles between diffuse- and intestinal-type gastric cancers using a genome-wide cDNA microarray.
Academic Article Analysis of gene-expression profiles in testicular seminomas using a genome-wide cDNA microarray.
Academic Article Novel tumor marker REG4 detected in serum of patients with resectable pancreatic cancer and feasibility for antibody therapy targeting REG4.
Academic Article Identification of a novel non-coding RNA, MIAT, that confers risk of myocardial infarction.
Academic Article Genome-wide analysis of gene expression in synovial sarcomas using a cDNA microarray.
Academic Article Genome-wide analysis of gene-expression profiles in chronic myeloid leukemia cells using a cDNA microarray.
Academic Article Association between genetic variation in the gene for death-associated protein-3 (DAP3) and adult asthma.
Academic Article Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction.
Academic Article Genome-wide analysis of gene expression in intestinal-type gastric cancers using a complementary DNA microarray representing 23,040 genes.
Academic Article Association of single-nucleotide polymorphisms in the polymeric immunoglobulin receptor gene with immunoglobulin A nephropathy (IgAN) in Japanese patients.
Academic Article Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis.
Academic Article Functional haplotypes of IL-12B are associated with childhood atopic asthma.
Academic Article A functional single nucleotide polymorphism in mucin 1, at chromosome 1q22, determines susceptibility to diffuse-type gastric cancer.
Academic Article Functional single-nucleotide polymorphisms in the secretogranin III (SCG3) gene that form secretory granules with appetite-related neuropeptides are associated with obesity.
Academic Article Comparative profiling of serum glycoproteome by sequential purification of glycoproteins and 2-nitrobenzensulfenyl (NBS) stable isotope labeling: a new approach for the novel biomarker discovery for cancer.
Academic Article Association of single-nucleotide polymorphisms in MTMR9 gene with obesity.
Academic Article A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.
Academic Article Association study of 71 European Crohn's disease susceptibility loci in a Japanese population.
Academic Article Predictive value of the IL28B polymorphism on the effect of interferon therapy in chronic hepatitis C patients with genotypes 2a and 2b.
Academic Article Influence of ITPA polymorphisms on decreases of hemoglobin during treatment with pegylated interferon, ribavirin, and telaprevir.
Academic Article An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis.
Academic Article Common variants in CASP3 confer susceptibility to Kawasaki disease.
Academic Article The textile plot: a new linkage disequilibrium display of multiple-single nucleotide polymorphism genotype data.
Academic Article Identification of 45 novel SNPs in the 83-kb region containing peptidylarginine deiminase types 1 and 3 loci on chromosomal band 1p36.13.
Academic Article Association of a single-nucleotide polymorphism in the immunoglobulin mu-binding protein 2 gene with immunoglobulin A nephropathy.
Academic Article High-density association study and nomination of susceptibility genes for hypertension in the Japanese National Project.
Academic Article Variations in the FTO gene are associated with severe obesity in the Japanese.
Academic Article A comprehensive peptidome profiling technology for the identification of early detection biomarkers for lung adenocarcinoma.
Academic Article INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese.
Academic Article Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk.
Academic Article Association of new loci identified in European genome-wide association studies with susceptibility to type 2 diabetes in the Japanese.
Academic Article Characterization of an Opa interacting protein 5 involved in lung and esophageal carcinogenesis.
Academic Article A genome-wide association study identifies a genetic variant in the SIAH2 locus associated with hormonal receptor-positive breast cancer in Japanese.
Academic Article Discovery and fine mapping of serum protein loci through transethnic meta-analysis.
Academic Article Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker.
Academic Article Impact of PSCA variation on gastric ulcer susceptibility.
Academic Article Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene.
Academic Article A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities.
Academic Article Association of the RIP2 gene with childhood atopic asthma.
Academic Article Targeted serum glycoproteomics for the discovery of lung cancer-associated glycosylation disorders using lectin-coupled ProteinChip arrays.
Academic Article Regulatory polymorphisms in EGR2 are associated with susceptibility to systemic lupus erythematosus.
Academic Article Polypeptide N-acetylgalactosaminyltransferase 6 disrupts mammary acinar morphogenesis through O-glycosylation of fibronectin.
Academic Article A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region.
Academic Article Histidine augments the suppression of hepatic glucose production by central insulin action.
Academic Article TSPYL5 SNPs: association with plasma estradiol concentrations and aromatase expression.
Academic Article Identification of a functional variant in SPLUNC1 associated with nasopharyngeal carcinoma susceptibility among Malaysian Chinese.
Academic Article Regulation of histone modification and chromatin structure by the p53-PADI4 pathway.
Academic Article Important and critical scientific aspects in pharmacogenomics analysis: lessons from controversial results of tamoxifen and CYP2D6 studies.
Academic Article High-density genotyping study identifies four new susceptibility loci for atopic dermatitis.
Academic Article Genome-wide analysis of organ-preferential metastasis of human small cell lung cancer in mice.
Academic Article Analysis of single-nucleotide polymorphisms in Japanese rheumatoid arthritis patients shows additional susceptibility markers besides the classic shared epitope susceptibility sequences.
Academic Article Genome-wide cDNA microarray analysis of gene expression profiles in pancreatic cancers using populations of tumor cells and normal ductal epithelial cells selected for purity by laser microdissection.
Academic Article Association of the gene encoding wingless-type mammary tumor virus integration-site family member 5B (WNT5B) with type 2 diabetes.
Academic Article A functional polymorphism in the 5' UTR of GDF5 is associated with susceptibility to osteoarthritis.
Academic Article Genetic variation in PSCA is associated with susceptibility to diffuse-type gastric cancer.
Academic Article Novel lipogenic enzyme ELOVL7 is involved in prostate cancer growth through saturated long-chain fatty acid metabolism.
Academic Article Toward the establishment of a prediction system for the personalized treatment of chronic hepatitis C.
Academic Article Whole-genome-wide association study in the Bulgarian population reveals HHAT as schizophrenia susceptibility gene.
Academic Article Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer.
Academic Article Lysyl 5-hydroxylation, a novel histone modification, by Jumonji domain containing 6 (JMJD6).
Academic Article An association analysis of HLA-DRB1 with systemic lupus erythematosus and rheumatoid arthritis in a Japanese population: effects of *09:01 allele on disease phenotypes.
Academic Article Seven new loci associated with age-related macular degeneration.
Academic Article Pathway analysis of genome-wide data improves warfarin dose prediction.
Academic Article Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer.
Academic Article A replication study for three nephrolithiasis loci at 5q35.3, 7p14.3 and 13q14.1 in the Japanese population.
Academic Article Critical role of lysine 134 methylation on histone H2AX for ?-H2AX production and DNA repair.
Academic Article Cell-permeable peptide DEPDC1-ZNF224 interferes with transcriptional repression and oncogenicity in bladder cancer cells.
Academic Article Tumor suppressive role of a 2.4 Mb 9q33-q34 critical region and DEC1 in esophageal squamous cell carcinoma.
Academic Article Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
Academic Article CD40 ligand gene and Kawasaki disease.
Academic Article DKK1, a negative regulator of Wnt signaling, is a target of the beta-catenin/TCF pathway.
Academic Article Isolation and characterization of a novel human gene, VANGL1, as a therapeutic target for hepatocellular carcinoma.
Academic Article Functional analysis of the thymic stromal lymphopoietin variants in human bronchial epithelial cells.
Academic Article Identification of Myc-associated protein with JmjC domain as a novel therapeutic target oncogene for lung cancer.
Academic Article Variation in the gene encoding Krüppel-like factor 7 influences body fat: studies of 14 818 Danes.
Academic Article Association analysis of SLC22A4, SLC22A5 and DLG5 in Japanese patients with Crohn disease.
Academic Article Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1.
Academic Article Wnt inhibitor Dickkopf-1 as a target for passive cancer immunotherapy.
Academic Article Osteopenia and male-specific sudden cardiac death in mice lacking a zinc transporter gene, Znt5.
Academic Article Potential involvement of p53 in ischemia/reperfusion-induced osteonecrosis.
Academic Article Thymic stromal lymphopoietin gene promoter polymorphisms are associated with susceptibility to bronchial asthma.
Academic Article A functional SNP in ITIH3 is associated with susceptibility to myocardial infarction.
Academic Article Non-transmissible Sendai virus encoding granulocyte macrophage colony-stimulating factor is a novel and potent vector system for producing autologous tumor vaccines.
Academic Article Aberrant laminin beta3 isoforms downstream of EWS-ETS fusion genes in Ewing family tumors.
Academic Article In vivo therapeutic effect of CDH3/P-cadherin-targeting radioimmunotherapy.
Academic Article Indazole-based potent and cell-active Mps1 kinase inhibitors: rational design from pan-kinase inhibitor anthrapyrazolone (SP600125).
Academic Article Host molecular defense mechanisms against Chlamydophila pneumoniae and genetic studies of immune-response-related genes in asthma.
Academic Article Late Cornified Envelope Group I, a novel target of p53, regulates PRMT5 activity.
Academic Article Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia.
Academic Article Genome-wide association study identified SNP on 15q24 associated with bladder cancer risk in Japanese population.
Academic Article Identification of promiscuous KIF20A long peptides bearing both CD4+ and CD8+ T-cell epitopes: KIF20A-specific CD4+ T-cell immunity in patients with malignant tumor.
Academic Article Up-regulation of PSF2, a member of the GINS multiprotein complex, in intrahepatic cholangiocarcinoma.
Academic Article Vaccination with multiple peptides derived from novel cancer-testis antigens can induce specific T-cell responses and clinical responses in advanced esophageal cancer.
Academic Article SNPs in BRAP associated with risk of myocardial infarction in Asian populations.
Academic Article Glypican-3, overexpressed specifically in human hepatocellular carcinoma, is a novel tumor marker.
Academic Article CLCA2 as a p53-inducible senescence mediator.
Academic Article Impact of allele copy number of polymorphisms in FCGR3A and FCGR3B genes on susceptibility to ulcerative colitis.
Academic Article Comparison of clinical features between suspected familial colorectal cancer type X and Lynch syndrome in Japanese patients with colorectal cancer: a cross-sectional study conducted by the Japanese Society for Cancer of the Colon and Rectum.
Academic Article Deficiency of GMDS leads to escape from NK cell-mediated tumor surveillance through modulation of TRAIL signaling.
Academic Article A polygenic risk score for breast cancer in women receiving tamoxifen or raloxifene on NSABP P-1 and P-2.
Academic Article Demethylation of RB regulator MYPT1 by histone demethylase LSD1 promotes cell cycle progression in cancer cells.
Academic Article Therapeutic potential of antibodies against FZD 10, a cell-surface protein, for synovial sarcomas.
Academic Article A functional SNP in CILP, encoding cartilage intermediate layer protein, is associated with susceptibility to lumbar disc disease.
Academic Article Loss of heterozygosity at the CYP2D6 locus in breast cancer: implications for germline pharmacogenetic studies.
Academic Article A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients.
Academic Article Relationship between smoking and multiple colorectal cancers in patients with Japanese Lynch syndrome: a cross-sectional study conducted by the Japanese Society for Cancer of the Colon and Rectum.
Academic Article Polymorphisms in the 3' UTR in the neurocalcin delta gene affect mRNA stability, and confer susceptibility to diabetic nephropathy.
Academic Article WDRPUH, a novel WD-repeat-containing protein, is highly expressed in human hepatocellular carcinoma and involved in cell proliferation.
Academic Article Orphan receptor tyrosine kinase ROR2 as a potential therapeutic target for osteosarcoma.
Academic Article Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.
Academic Article Plasma low-molecular-weight proteome profiling identified neuropeptide-Y as a prostate cancer biomarker polypeptide.
Academic Article The lysine 831 of vascular endothelial growth factor receptor 1 is a novel target of methylation by SMYD3.
Academic Article Association of EMCN with susceptibility to rheumatoid arthritis in a Japanese population.
Academic Article Tumor budding is a significant indicator of a poor prognosis in lung squamous cell carcinoma patients.
Academic Article Identification of immunoglobulin superfamily 11 (IGSF11) as a novel target for cancer immunotherapy of gastrointestinal and hepatocellular carcinomas.
Academic Article A novel tumor-associated antigen, cell division cycle 45-like can induce cytotoxic T-lymphocytes reactive to tumor cells.
Academic Article Coding SNP in tenascin-C Fn-III-D domain associates with adult asthma.
Academic Article Germline variants and advanced colorectal adenomas: adenoma prevention with celecoxib trial genome-wide association study.
Academic Article A unique hinge binder of extremely selective aminopyridine-based Mps1 (TTK) kinase inhibitors with cellular activity.
Academic Article Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP pools.
Academic Article Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease.
Academic Article Involvement of the FGF18 gene in colorectal carcinogenesis, as a novel downstream target of the beta-catenin/T-cell factor complex.
Academic Article No association for Chinese HBV-related hepatocellular carcinoma susceptibility SNP in other East Asian populations.
Academic Article The BioBank Japan Project.
Academic Article Inhibition of tumor growth through suppression of angiogenesis by brain-specific angiogenesis inhibitor 1 gene transfer in murine renal cell carcinoma.
Academic Article Recombination rates of genes expressed in human tissues.
Academic Article Identification of candidate predictive markers of anticancer drug sensitivity using a panel of human cancer cell lines.
Academic Article Radioimmunotherapy of human synovial sarcoma using a monoclonal antibody against FZD10.
Academic Article Identification of nectin-4 oncoprotein as a diagnostic and therapeutic target for lung cancer.
Academic Article Determination of splice-site mutations in Lynch syndrome (hereditary non-polyposis colorectal cancer) patients using functional splicing assay.
Academic Article Cystatin 10, a novel chondrocyte-specific protein, may promote the last steps of the chondrocyte differentiation pathway.
Academic Article Genome-wide association study identifies a new SMAD7 risk variant associated with colorectal cancer risk in East Asians.
Academic Article HLA-DQB1*03 confers susceptibility to chronic hepatitis C in Japanese: a genome-wide association study.
Academic Article The construction of risk prediction models using GWAS data and its application to a type 2 diabetes prospective cohort.
Academic Article Impact of viral amino acid substitutions and host interleukin-28b polymorphism on replication and susceptibility to interferon of hepatitis C virus.
Academic Article Activation of an oncogenic TBC1D7 (TBC1 domain family, member 7) protein in pulmonary carcinogenesis.
Academic Article A functional SNP in the NKX2.5-binding site of ITPR3 promoter is associated with susceptibility to systemic lupus erythematosus in Japanese population.
Academic Article Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stresses.
Academic Article Identification of TOMM34, which shows elevated expression in the majority of human colon cancers, as a novel drug target.
Academic Article Single-nucleotide polymorphisms in GALNT8 are associated with the response to interferon therapy for chronic hepatitis C.
Academic Article Association between single-nucleotide polymorphisms in selectin genes and immunoglobulin A nephropathy.
Academic Article VAV3 mediates resistance to breast cancer endocrine therapy.
Academic Article HLA-A SNPs and amino acid variants are associated with nasopharyngeal carcinoma in Malaysian Chinese.
Academic Article A functional SNP in EDG2 increases susceptibility to knee osteoarthritis in Japanese.
Academic Article A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese.
Academic Article Adenovirus-mediated p53AIP1 gene transfer as a new strategy for treatment of p53-resistant tumors.
Academic Article A phase I study of combination vaccine treatment of five therapeutic epitope-peptides for metastatic colorectal cancer; safety, immunological response, and clinical outcome.
Academic Article A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells.
Academic Article Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro.
Academic Article Identification of secernin 1 as a novel immunotherapy target for gastric cancer using the expression profiles of cDNA microarray.
Academic Article Association of STAT4 with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in the Japanese population.
Academic Article A single nucleotide polymorphism within the acetyl-coenzyme A carboxylase beta gene is associated with proteinuria in patients with type 2 diabetes.
Academic Article Identification of SPARC as a candidate target antigen for immunotherapy of various cancers.
Academic Article Serial analysis of gene expression in progressing and regressing mouse tumors implicates the involvement of RANTES and TARC in antitumor immune responses.
Academic Article Identification of p53-46F as a super p53 with an enhanced ability to induce p53-dependent apoptosis.
Academic Article A functional SNP in PSMA6 confers risk of myocardial infarction in the Japanese population.
Academic Article Associations of HLA-DP variants with hepatitis B virus infection in southern and northern Han Chinese populations: a multicenter case-control study.
Academic Article An algorithm for inferring complex haplotypes in a region of copy-number variation.
Academic Article Isolation of LEM domain-containing 1, a novel testis-specific gene expressed in colorectal cancers.
Academic Article New correction algorithms for multiple comparisons in case-control multilocus association studies based on haplotypes and diplotype configurations.
Academic Article SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells.
Academic Article An association study of asthma and related phenotypes with polymorphisms in negative regulator molecules of the TLR signaling pathway.
Academic Article FCRL3, an autoimmune susceptibility gene, has inhibitory potential on B-cell receptor-mediated signaling.
Academic Article Isolation of development and differentiation enhancing factor-like 1 (DDEFL1) as a drug target for hepatocellular carcinomas.
Academic Article Large-scale single-nucleotide polymorphism (SNP) and haplotype analyses, using dense SNP Maps, of 199 drug-related genes in 752 subjects: the analysis of the association between uncommon SNPs within haplotype blocks and the haplotypes constructed with haplotype-tagging SNPs.
Academic Article TOPK inhibitor induces complete tumor regression in xenograft models of human cancer through inhibition of cytokinesis.
Academic Article Oncogenic role of KIAA0101 interacting with proliferating cell nuclear antigen in pancreatic cancer.
Academic Article Oncogenic role of MPHOSPH1, a cancer-testis antigen specific to human bladder cancer.
Academic Article Inhibition of experimental intimal thickening in mice lacking a novel G-protein-coupled receptor.
Academic Article SUV39H2 methylates and stabilizes LSD1 by inhibiting polyubiquitination in human cancer cells.
Academic Article T-LAK cell-originated protein kinase presents a novel therapeutic target in FLT3-ITD mutated acute myeloid leukemia.
Academic Article Regulation of iron homeostasis by the p53-ISCU pathway.
Academic Article Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity.
Academic Article HLA-A2-restricted CTL epitopes of a novel lung cancer-associated cancer testis antigen, cell division cycle associated 1, can induce tumor-reactive CTL.
Academic Article Identification of CDCA1-derived long peptides bearing both CD4+ and CD8+ T-cell epitopes: CDCA1-specific CD4+ T-cell immunity in cancer patients.
Academic Article Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion.
Academic Article Radioimmunotherapy of solid tumors targeting a cell-surface protein, FZD10: therapeutic efficacy largely depends on radiosensitivity.
Academic Article Herpes simplex virus-induced, death receptor-dependent apoptosis and regression of transplanted human cancers.
Academic Article Cystatin C as a p53-inducible apoptotic mediator that regulates cathepsin L activity.
Academic Article Characterization of T-cell Receptor Repertoire in Inflamed Tissues of Patients with Crohn's Disease Through Deep Sequencing.
Academic Article Serum tumor antigen REG4 as a diagnostic biomarker in pancreatic ductal adenocarcinoma.
Academic Article Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation.
Academic Article Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor.
Academic Article Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms.
Academic Article Integrated pathway analysis of nasopharyngeal carcinoma implicates the axonemal dynein complex in the Malaysian cohort.
Academic Article Epigenetic inactivation of the deleted in lung and esophageal cancer 1 gene in nasopharyngeal carcinoma.
Academic Article The forkhead box M1 transcription factor as a candidate of target for anti-cancer immunotherapy.
Academic Article Pharmacogenetic Discovery in CALGB (Alliance) 90401 and Mechanistic Validation of a VAC14 Polymorphism that Increases Risk of Docetaxel-Induced Neuropathy.
Academic Article Significant Effect of Polymorphisms in CYP2D6 on Response to Tamoxifen Therapy for Breast Cancer: A Prospective Multicenter Study.
Academic Article T-LAK Cell-Originated Protein Kinase (TOPK) as a Prognostic Factor and a Potential Therapeutic Target in Ovarian Cancer.
Academic Article Construction and characterization of a vestibular-specific cDNA library using T7-based RNA amplification.
Academic Article Quantitative T cell repertoire analysis by deep cDNA sequencing of T cell receptor a and ß chains using next-generation sequencing (NGS).
Academic Article Mutations in the gene encoding KIAA1199 protein, an inner-ear protein expressed in Deiters' cells and the fibrocytes, as the cause of nonsyndromic hearing loss.
Academic Article WHSC1L1-mediated EGFR mono-methylation enhances the cytoplasmic and nuclear oncogenic activity of EGFR in head and neck cancer.
Academic Article GALNT6 Stabilizes GRP78 Protein by O-glycosylation and Enhances its Activity to Suppress Apoptosis Under Stress Condition.
Academic Article Risk prediction models for mortality in patients with cardiovascular disease: The BioBank Japan project.
Academic Article Characterization of T cell repertoire of blood, tumor, and ascites in ovarian cancer patients using next generation sequencing.
Academic Article Quantitative characterization of T-cell repertoire and biomarkers in kidney transplant rejection.
Academic Article Cross-sectional analysis of BioBank Japan clinical data: A large cohort of 200,000 patients with 47 common diseases.
Academic Article Overview of BioBank Japan follow-up data in 32 diseases.
Academic Article Statin use and all-cause and cancer mortality: BioBank Japan cohort.
Academic Article Demographic and lifestyle factors and survival among patients with esophageal and gastric cancer: The Biobank Japan Project.
Academic Article Characteristics and prognosis of Japanese male and female lung cancer patients: The BioBank Japan Project.
Academic Article Characteristics and prognosis of Japanese female breast cancer patients: The BioBank Japan project.
Academic Article Survival of macrovascular disease, chronic kidney disease, chronic respiratory disease, cancer and smoking in patients with type 2 diabetes: BioBank Japan cohort.
Academic Article Clinical and histopathological characteristics of patients with prostate cancer in the BioBank Japan project.
Academic Article SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway.
Academic Article The Transcriptional Landscape of p53 Signalling Pathway.
Academic Article Third-generation oncolytic herpes simplex virus inhibits the growth of liver tumors in mice.
Academic Article Fukutin is required for maintenance of muscle integrity, cortical histiogenesis and normal eye development.
Academic Article The vitamin D receptor gene as a determinant of survival in pancreatic cancer patients: Genomic analysis and experimental validation.
Academic Article miR-125b-1 and miR-378a are predictive biomarkers for the efficacy of vaccine treatment against colorectal cancer.
Academic Article A phase I clinical trial of RNF43 peptide-related immune cell therapy combined with low-dose cyclophosphamide in patients with advanced solid tumors.
Academic Article GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12.
Academic Article Development of novel SUV39H2 inhibitors that exhibit growth suppressive effects in mouse xenograft models and regulate the phosphorylation of H2AX.
Academic Article Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: metabolomics-informed genomics.
Academic Article Citrullination of RGG Motifs in FET Proteins by PAD4 Regulates Protein Aggregation and ALS Susceptibility.
Academic Article a-particle therapy for synovial sarcoma in the mouse using an astatine-211-labeled antibody against frizzled homolog 10.
Academic Article Genome-wide association study identifies gastric cancer susceptibility loci at 12q24.11-12 and 20q11.21.
Academic Article Maternal Embryonic Leucine Zipper Kinase (MELK), a Potential Therapeutic Target for Neuroblastoma.
Academic Article Tamoxifen Metabolism and Breast Cancer Recurrence: A Question Unanswered by CYPTAM.
Academic Article Potent anti-myeloma activity of the TOPK inhibitor OTS514 in pre-clinical models.
Academic Article Identification of two novel breast cancer loci through large-scale genome-wide association study in the Japanese population.
Academic Article Dose escalation prophylactic donor lymphocyte infusion after T-cell depleted matched related donor allogeneic hematopoietic cell transplantation is feasible and results in higher donor chimerism, faster immune re-constitution, and prolonged progression-free survival.
Academic Article CMOS-based bio-image sensor spatially resolves neural activity-dependent proton dynamics in the living brain.
Academic Article Effect of CYP4F2, VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single-Patient Data Meta-Analysis in More Than 15,000 Individuals.
Academic Article Cooperation of genes in HPV16 E6/E7-dependent cervicovaginal carcinogenesis trackable by endoscopy and independent of exogenous estrogens or carcinogens.
Academic Article Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases.
Academic Article CD8 lymphocytes in tumors and nonsynonymous mutational load correlate with prognosis of bladder cancer patients treated with immune checkpoint inhibitors.
Academic Article Enhancement of Migration and Invasion of Gastric Cancer Cells by IQGAP3.
Academic Article Phase II Adjuvant Cancer-specific Vaccine Therapy for Esophageal Cancer Patients Curatively Resected After Preoperative Therapy With Pathologically Positive Nodes; Possible Significance of Tumor Immune Microenvironment in its Clinical Effects.
Academic Article Correction: Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor.
Academic Article Anti-cancer immunotherapy using cancer-derived multiple epitope-peptides cocktail vaccination clinical studies in patients with refractory/persistent disease of uterine cervical cancer and ovarian cancer [phase 2].
Academic Article Genome-wide association study of epilepsy in a Japanese population identified an associated region at chromosome 12q24.
Academic Article Generation of neoantigen-specific T cells for adoptive cell transfer for treating head and neck squamous cell carcinoma.
Academic Article Efficacy of Intranodal Neoantigen Peptide-pulsed Dendritic Cell Vaccine Monotherapy in Patients With Advanced Solid Tumors: A Retrospective Analysis.
Academic Article Contribution of pre-existing neoantigen-specific T cells to a durable complete response after tumor-pulsed dendritic cell vaccine plus nivolumab therapy in a patient with metastatic salivary duct carcinoma.
Academic Article Established fibrous peritoneal metastasis in an immunocompetent mouse model similar to clinical immune microenvironment of gastric cancer.
Academic Article A cross-population atlas of genetic associations for 220 human phenotypes.
Academic Article FZD10-targeted a-radioimmunotherapy with 225 Ac-labeled OTSA101 achieves complete remission in a synovial sarcoma model.
Academic Article Identification of cytotoxic T cells and their T cell receptor sequences targeting COVID-19 using MHC class I-binding peptides.
Academic Article Correction: Identification of cytotoxic T cells and their T cell receptor sequences targeting COVID-19 using MHC class I-binding peptides.
Academic Article Rapid genomic profiling of circulating tumor DNA in non-small cell lung cancer using Oncomine Precision Assay with Genexus™ integrated sequencer.
Academic Article Head-to-head comparison of three chelates reveals DOTAGA promising for 225 Ac labeling of anti-FZD10 antibody OTSA101.
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